Trisomy 13 :
-absence of the olfactory nerve or bulb ;
-severe eye defects (microphtalmia , coboloma , cyclopism) ;
-deafness ;
-cleft lip/palate ;
-omphalocele , umbilical hernia ;
-genitourinary abnormalities ;
-polydactyly ;
-superficial hemangiomas ;
-club feet ;
-cardiac defects .